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Papers authored by Akira S

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IPS-1 is crucial for DAP3-mediated anoikis induction by caspase-8 activation.

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Li HM, Fujikura D, Harada T, Uehara J, Kawai T, Akira S, Reed JC, Iwai A, and Miyazaki T

Cell death and differentiation 16(12):1615-21, 2009 Dec - Who cited this? | PubMed ID: 19644511 | Fulltext

Differential Involvement of Atg16L1 in Crohn Disease and Canonical Autophagy: ANALYSIS OF THE ORGANIZATION OF THE Atg16L1 COMPLEX IN FIBROBLASTS.

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Fujita N, Saitoh T, Kageyama S, Akira S, Noda T, and Yoshimori T

The Journal of biological chemistry 284(47):32602-9, 2009 Nov 20 - Who cited this? | PubMed ID: 19783656 | Fulltext

HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses.

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Yanai H, Ban T, Wang Z, Choi MK, Kawamura T, Negishi H, Nakasato M, Lu Y, Hangai S, Koshiba R, Savitsky D, Ronfani L, Akira S, Bianchi ME, Honda K, Tamura T,

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Nature 462(7269):99-103, 2009 Nov 5 - Who cited this? | PubMed ID: 19890330 | Fulltext

Type I interferon modulates monocyte recruitment and maturation in chronic inflammation.

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Lee PY, Li Y, Kumagai Y, Xu Y, Weinstein JS, Kellner ES, Nacionales DC, Butfiloski EJ, van Rooijen N, Akira S, Sobel ES, Satoh M, and Reeves WH

The American journal of pathology 175(5):2023-33, 2009 Nov - Who cited this? | PubMed ID: 19808647 | Fulltext

Increased atherosclerotic lesions and Th17 in interleukin-18 deficient apolipoprotein E-knockout mice fed high-fat diet.

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Pejnovic N, Vratimos A, Lee SH, Popadic D, Takeda K, Akira S, and Chan WL

Molecular immunology 47(1):37-45, 2009 Nov - Who cited this? | PubMed ID: 19201478 | Fulltext

[Control of inflammatory responses by a novel RNase, Zc3h12a].

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Takeuchi O, Matsushita K, and Akira S

Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 54(14):1837-41, 2009 Nov - Who cited this? | PubMed ID: 19894584 | Fulltext

[Regulation of allergy by innate immune system].

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Kumagai Y and Akira S

Nippon rinsho. Japanese journal of clinical medicine 67(11):2055-61, 2009 Nov - Who cited this? | PubMed ID: 19899516 | Fulltext

Toll-like receptors and innate immunity.

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Kumar H, Kawai T, and Akira S

Biochemical and biophysical research communications 388(4):621-5, 2009 Oct 30 - Who cited this? | PubMed ID: 19686699 | Fulltext

Id2-, ROR{gamma}t-, and LT{beta}R-independent initiation of lymphoid organogenesis in ocular immunity.

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Nagatake T, Fukuyama S, Kim DY, Goda K, Igarashi O, Sato S, Nochi T, Sagara H, Yokota Y, Jetten AM, Kaisho T, Akira S, Mimuro H, Sasakawa C, Fukui Y, Fujihashi K,

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The Journal of experimental medicine 206(11):2351-64, 2009 Oct 26 - Who cited this? | PubMed ID: 19822644 | Fulltext

The viral RNA recognition sensor RIG-I is degraded during encephalomyocarditis virus (EMCV) infection.

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Papon L, Oteiza A, Imaizumi T, Kato H, Brocchi E, Lawson TG, Akira S, and Mechti N

Virology 393(2):311-8, 2009 Oct 25 - Who cited this? | PubMed ID: 19733381 | Fulltext

Absence of functional Hfe protects mice from invasive Salmonella enterica Serovar Typhimurium infection via induction of lipocalin-2.

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Nairz M, Theurl I, Schroll A, Theurl M, Fritsche G, Lindner E, Seifert M, Crouch ML, Hantke K, Akira S, Fang FC, and Weiss G

Blood 114(17):3642-51, 2009 Oct 22 - Who cited this? | PubMed ID: 19700664 | Fulltext

A selective contribution of the RIG-I-like receptor pathway to type I interferon responses activated by cytosolic DNA.

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Choi MK, Wang Z, Ban T, Yanai H, Lu Y, Koshiba R, Nakaima Y, Hangai S, Savitsky D, Nakasato M, Negishi H, Takeuchi O, Honda K, Akira S, Tamura T, and Taniguchi T

Proceedings of the National Academy of Sciences of the United States of America 106(42):17870-5, 2009 Oct 20 - Who cited this? | PubMed ID: 19805092 | Fulltext

Activation of MDA5 requires higher-order RNA structures generated during virus infection.

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Pichlmair A, Schulz O, Tan CP, Rehwinkel J, Kato H, Takeuchi O, Akira S, Way M, Schiavo G, and Reis e Sousa C

Journal of virology 83(20):10761-9, 2009 Oct - Who cited this? | PubMed ID: 19656871 | Fulltext

Systemic endotoxin induces gene expression of inducible nitric oxide synthase in fetal rat brain.

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Igarashi K, Akira S, Imaki J, and Takeshita T

Journal of Nippon Medical School = Nihon Ika Daigaku zasshi 76(5):232-9, 2009 Oct - Who cited this? | PubMed ID: 19915306 | Fulltext

TANK is a negative regulator of Toll-like receptor signaling and is critical for the prevention of autoimmune nephritis.

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Kawagoe T, Takeuchi O, Takabatake Y, Kato H, Isaka Y, Tsujimura T, and Akira S

Nature immunology 10(9):965-72, 2009 Sep - Who cited this? | PubMed ID: 19668221 | Fulltext

Requirement for DNA CpG content in TLR9-dependent dendritic cell activation induced by DNA-containing immune complexes.

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Yasuda K, Richez C, Uccellini MB, Richards RJ, Bonegio RG, Akira S, Monestier M, Corley RB, Viglianti GA, Marshak-Rothstein A, and Rifkin IR

Journal of immunology (Baltimore, Md. : 1950) 183(5):3109-17, 2009 Sep 1 - Who cited this? | PubMed ID: 19648272 | Fulltext

A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP.

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McWhirter SM, Barbalat R, Monroe KM, Fontana MF, Hyodo M, Joncker NT, Ishii KJ, Akira S, Colonna M, Chen ZJ, Fitzgerald KA, Hayakawa Y, and Vance RE

The Journal of experimental medicine 206(9):1899-911, 2009 Aug 31 - Who cited this? | PubMed ID: 19652017 | Fulltext

Augmented TLR9-induced Btk activation in PIR-B-deficient B-1 cells provokes excessive autoantibody production and autoimmunity.

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Kubo T, Uchida Y, Watanabe Y, Abe M, Nakamura A, Ono M, Akira S, and Takai T

The Journal of experimental medicine 206(9):1971-82, 2009 Aug 31 - Who cited this? | PubMed ID: 19687229 | Fulltext

Poly I:C-induced activation of NK cells by CD8alpha+ dendritic cells via the IPS-1 and TRIF-dependent pathways.

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Miyake T, Kumagai Y, Kato H, Guo Z, Matsushita K, Satoh T, Kawagoe T, Kumar H, Jang MH, Kawai T, Tani T, Takeuchi O, and Akira S

Journal of immunology (Baltimore, Md. : 1950) 183(4):2522-8, 2009 Aug 15 - Who cited this? | PubMed ID: 19635904 | Fulltext

Contribution of TIR domain-containing adapter inducing IFN-beta-mediated IL-18 release to LPS-induced liver injury in mice.

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Imamura M, Tsutsui H, Yasuda K, Uchiyama R, Yumikura-Futatsugi S, Mitani K, Hayashi S, Akira S, Taniguchi S, Van Rooijen N, Tschopp J, Yamamoto T, Fujimoto J, and Nakanishi K

Journal of hepatology 51(2):333-41, 2009 Aug - Who cited this? | PubMed ID: 19501931 | Fulltext

Baculovirus Induces Type I Interferon Production through Toll-Like Receptor-Dependent and -Independent Pathways in a Cell-Type-Specific Manner.

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Abe T, Kaname Y, Wen X, Tani H, Moriishi K, Uematsu S, Takeuchi O, Ishii KJ, Kawai T, Akira S, and Matsuura Y

Journal of virology 83(15):7629-40, 2009 Aug - Who cited this? | PubMed ID: 19474102 | Fulltext

Innate immune control of nucleic acid-based vaccine immunogenicity.

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Koyama S, Coban C, Aoshi T, Horii T, Akira S, and Ishii KJ

Expert review of vaccines 8(8):1099-107, 2009 Aug - Who cited this? | PubMed ID: 19627190 | Fulltext

Lipopolysaccharide inhibition of glucose production through the Toll-like receptor-4, myeloid differentiation factor 88, and nuclear factor kappab pathway.

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Raetzsch CF, Brooks NL, Alderman JM, Moore KS, Hosick PA, Klebanov S, Akira S, Bear JE, Baldwin AS, Mackman N, and Combs TP

Hepatology (Baltimore, Md.) 50(2):592-600, 2009 Aug - Who cited this? | PubMed ID: 19492426 | Fulltext

Analysis of binding site for the novel small-molecule TLR4 signal transduction inhibitor TAK-242 and its therapeutic effect on mouse sepsis model.

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Takashima K, Matsunaga N, Yoshimatsu M, Hazeki K, Kaisho T, Uekata M, Hazeki O, Akira S, Iizawa Y, and Ii M

British journal of pharmacology 157(7):1250-62, 2009 Aug - Who cited this? | PubMed ID: 19563534 | Fulltext

Proteomic analyses of recombinant human follicle-stimulating hormone and urinary-derived gonadotropin preparations.

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Kuwabara Y, Mine K, Katayama A, Inagawa T, Akira S, and Takeshita T

The Journal of reproductive medicine 54(8):459-66, 2009 Aug - Who cited this? | PubMed ID: 19769189 | Fulltext

Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus.

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Schlee M, Roth A, Hornung V, Hagmann CA, Wimmenauer V, Barchet W, Coch C, Janke M, Mihailovic A, Wardle G, Juranek S, Kato H, Kawai T, Poeck H, Fitzgerald KA, Takeuchi O,

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Immunity 31(1):25-34, 2009 Jul 17 - Who cited this? | PubMed ID: 19576794 | Fulltext

Toll-like receptor 9-dependent activation of myeloid dendritic cells by Deoxynucleic acids from Candida albicans.

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Miyazato A, Nakamura K, Yamamoto N, Mora-Montes HM, Tanaka M, Abe Y, Tanno D, Inden K, Gang X, Ishii K, Takeda K, Akira S, Saijo S, Iwakura Y, Adachi Y, Ohno N,

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Infection and immunity 77(7):3056-64, 2009 Jul - Who cited this? | PubMed ID: 19433551 | Fulltext

Downstream signals for MyD88-mediated phagocytosis of Borrelia burgdorferi can be initiated by TRIF and are dependent on PI3K.

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Shin OS, Miller LS, Modlin RL, Akira S, Uematsu S, and Hu LT

Journal of immunology (Baltimore, Md. : 1950) 183(1):491-8, 2009 Jul 1 - Who cited this? | PubMed ID: 19542460 | Fulltext

PolyI:C-induced reduction in uptake of soluble antigen is independent of dendritic cell activation.

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Tirapu I, Giquel B, Alexopoulou L, Uematsu S, Flavell R, Akira S, and Diebold SS

International immunology 21(7):871-9, 2009 Jul - Who cited this? | PubMed ID: 19505890 | Fulltext

NFATc1 mediates Toll-like receptor-independent innate immune responses during Trypanosoma cruzi infection.

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Kayama H, Koga R, Atarashi K, Okuyama M, Kimura T, Mak TW, Uematsu S, Akira S, Takayanagi H, Honda K, Yamamoto M, and Takeda K

PLoS pathogens 5(7):e1000514, 2009 Jul - Who cited this? | PubMed ID: 19609356 | Fulltext

Direct stimulation of tlr5+/+ CD11c+ cells is necessary for the adjuvant activity of flagellin.

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Bates JT, Uematsu S, Akira S, and Mizel SB

Journal of immunology (Baltimore, Md. : 1950) 182(12):7539-47, 2009 Jun 15 - Who cited this? | PubMed ID: 19494277 | Fulltext

Toll-like receptor 2 is critical for induction of Reg3{beta} expression and intestinal clearance of Yersinia pseudotuberculosis.

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Dessein R, Gironella M, Vignal C, Peyrin-Biroulet L, Sokol H, Secher T, Lacas-Gervais S, Gratadoux JJ, Lafont F, Dagorn JC, Ryffel B, Akira S, Langella P, Nùñez G, Sirard JC, Iovanna J,

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Gut 58(6):771-6, 2009 Jun - Who cited this? | PubMed ID: 19174417 | Fulltext

Differential role for c-Rel and C/EBPbeta/delta in TLR-mediated induction of proinflammatory cytokines.

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Lu YC, Kim I, Lye E, Shen F, Suzuki N, Suzuki S, Gerondakis S, Akira S, Gaffen SL, Yeh WC, and Ohashi PS

Journal of immunology (Baltimore, Md. : 1950) 182(11):7212-21, 2009 Jun 1 - Who cited this? | PubMed ID: 19454718 | Fulltext

Bacterial recognition by TLR7 in the lysosomes of conventional dendritic cells.

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Mancuso G, Gambuzza M, Midiri A, Biondo C, Papasergi S, Akira S, Teti G, and Beninati C

Nature immunology 10(6):587-94, 2009 Jun - Who cited this? | PubMed ID: 19430477 | Fulltext

Role of p38 and early growth response factor 1 in the macrophage response to group B streptococcus.

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Kenzel S, Santos-Sierra S, Deshmukh SD, Moeller I, Ergin B, Fitzgerald KA, Lien E, Akira S, Golenbock DT, and Henneke P

Infection and immunity 77(6):2474-81, 2009 Jun - Who cited this? | PubMed ID: 19332535 | Fulltext

Radioresistant cells expressing TLR5 control the respiratory epithelium's innate immune responses to flagellin.

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Janot L, Sirard JC, Secher T, Noulin N, Fick L, Akira S, Uematsu S, Didierlaurent A, Hussell T, Ryffel B, and Erard F

European journal of immunology 39(6):1587-96, 2009 Jun - Who cited this? | PubMed ID: 19424969 | Fulltext

Innate Immune Sensing of Modified Vaccinia Virus Ankara (MVA) Is Mediated by TLR2-TLR6, MDA-5 and the NALP3 Inflammasome.

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Delaloye J, Roger T, Steiner-Tardivel QG, Le Roy D, Knaup Reymond M, Akira S, Petrilli V, Gomez CE, Perdiguero B, Tschopp J, Pantaleo G, Esteban M, and Calandra T

PLoS pathogens 5(6):e1000480, 2009 Jun - Who cited this? | PubMed ID: 19543380 | Fulltext

iNOS-Producing Inflammatory Dendritic Cells Constitute the Major Infected Cell Type during the Chronic Leishmania major Infection Phase of C57BL/6 Resistant Mice.

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De Trez C, Magez S, Akira S, Ryffel B, Carlier Y, and Muraille E

PLoS pathogens 5(6):e1000494, 2009 Jun - Who cited this? | PubMed ID: 19557162 | Fulltext

[Frontiers of research on innate immunity.].

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Kumagai Y, Saitoh T, and Akira S

Arerugi = [Allergy] 58(6):638-47, 2009 Jun - Who cited this? | PubMed ID: 19571657 | Fulltext

Pathogen recognition in the innate immune response.

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Kumar H, Kawai T, and Akira S

The Biochemical journal 420(1):1-16, 2009 May 15 - Who cited this? | PubMed ID: 19382893 | Fulltext

Toll-like receptor 3 enhances late-phase reaction of experimental allergic conjunctivitis.

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Ueta M, Uematsu S, Akira S, and Kinoshita S

The Journal of allergy and clinical immunology 123(5):1187-9, 2009 May - Who cited this? | PubMed ID: 19362356 | Fulltext

Zc3h12a is an RNase essential for controlling immune responses by regulating mRNA decay.

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Matsushita K, Takeuchi O, Standley DM, Kumagai Y, Kawagoe T, Miyake T, Satoh T, Kato H, Tsujimura T, Nakamura H, and Akira S

Nature 458(7242):1185-90, 2009 Apr 30 - Who cited this? | PubMed ID: 19322177 | Fulltext

Toll-like receptor 2 deficiency is associated with enhanced severity of group B streptococcal disease.

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Puliti M, Uematsu S, Akira S, Bistoni F, and Tissi L

Infection and immunity 77(4):1524-31, 2009 Apr - Who cited this? | PubMed ID: 19179417 | Fulltext

Irinotecan-induced ovarian follicular apoptosis is attenuated by deleting the kinase domain of death-associated protein kinase.

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Li L, Tanaka T, Yukawa K, Akira S, and Umesaki N

International journal of oncology 34(4):905-14, 2009 Apr - Who cited this? | PubMed ID: 19287947 | Fulltext

Cutting Edge: TLR-Dependent viral recognition along with type I IFN positive feedback signaling masks the requirement of viral replication for IFN-{alpha} production in plasmacytoid dendritic cells.

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Kumagai Y, Kumar H, Koyama S, Kawai T, Takeuchi O, and Akira S

Journal of immunology (Baltimore, Md. : 1950) 182(7):3960-4, 2009 Apr 1 - Who cited this? | PubMed ID: 19299691 | Fulltext

Ncf1 provides a reactive oxygen species-independent negative feedback regulation of TLR9-induced IL-12p70 in murine dendritic cells.

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Richter C, Juan MH, Will J, Brandes RP, Kalinke U, Akira S, Pfeilschifter JM, Hultqvist M, Holmdahl R, and Radeke HH

Journal of immunology (Baltimore, Md. : 1950) 182(7):4183-91, 2009 Apr 1 - Who cited this? | PubMed ID: 19299716 | Fulltext

Trif is not required for immune complex glomerulonephritis: dying cells activate mesangial cells via Tlr2/Myd88 rather than Tlr3/Trif.

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Lichtnekert J, Vielhauer V, Zecher D, Kulkarni OP, Clauss S, Segerer S, Hornung V, Mayadas TN, Beutler B, Akira S, and Anders HJ

American journal of physiology. Renal physiology 296(4):F867-74, 2009 Apr - Who cited this? | PubMed ID: 19158348 | Fulltext

Toll-like receptor 7 cooperates with IL-4 in activated B cells through antigen receptor or CD38 and induces class switch recombination and IgG1 production.

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Tsukamoto Y, Nagai Y, Kariyone A, Shibata T, Kaisho T, Akira S, Miyake K, and Takatsu K

Molecular immunology 46(7):1278-88, 2009 Apr - Who cited this? | PubMed ID: 19157556 | Fulltext

The roles of TLRs, RLRs and NLRs in pathogen recognition.

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Kawai T and Akira S

International immunology 21(4):317-37, 2009 Apr - Who cited this? | PubMed ID: 19246554 | Fulltext

Pivotal Advance: Toll-like receptor regulation of scavenger receptor-A-mediated phagocytosis.

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Amiel E, Alonso A, Uematsu S, Akira S, Poynter ME, and Berwin B

Journal of leukocyte biology 85(4):595-605, 2009 Apr - Who cited this? | PubMed ID: 19112093 | Fulltext

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Papers authored by Akira S

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