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Papers authored by Akanuma S

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Characteristics of glycine transport across the inner blood-retinal barrier.

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Okamoto M, Akanuma S, Tachikawa M, and Hosoya K

Neurochemistry international 55(8):789-95, 2009 Dec - Who cited this? | PubMed ID: 19666071 | Fulltext

Cationic amino acid transporter 1-mediated l-arginine transport at the inner blood-retinal barrier.

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Tomi M, Kitade N, Hirose S, Yokota N, Akanuma S, Tachikawa M, and Hosoya K

Journal of neurochemistry 111(3):716-25, 2009 Nov - Who cited this? | PubMed ID: 19712052 | Fulltext

High-Density Lipoprotein-Associated alpha-Tocopherol Uptake by Human Retinal Pigment Epithelial Cells (ARPE-19 Cells): the Irrelevance of Scavenger Receptor Class B, Type I.

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Akanuma S, Yamamoto A, Okayasu S, Tachikawa M, and Hosoya K

Biological & pharmaceutical bulletin 32(6):1131-4, 2009 Jun - Who cited this? | PubMed ID: 19483330 | Fulltext

Roles of Inner Blood-Retinal Barrier Organic Anion Transporter 3 in the Vitreous/Retina-to-Blood Efflux Transport of p-Aminohippuric Acid, Benzylpenicillin, and 6-Mercaptopurine.

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Hosoya K, Makihara A, Tsujikawa Y, Yoneyama D, Mori S, Terasaki T, Akanuma S, Tomi M, and Tachikawa M

The Journal of pharmacology and experimental therapeutics 329(1):87-93, 2009 Apr - Who cited this? | PubMed ID: 19116370 | Fulltext

Random mutagenesis improves the low-temperature activity of the tetrameric 3-isopropylmalate dehydrogenase from the hyperthermophile Sulfolobus tokodaii.

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Sasaki M, Uno M, Akanuma S, and Yamagishi A

Protein engineering, design & selection : PEDS, 2008 Oct 14 - Who cited this? | PubMed ID: 18854331 | Fulltext

Experimental Evidence for the Existence of a Stable Half-Barrel Subdomain in the (beta/alpha)(8)-Barrel Fold.

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Akanuma S and Yamagishi A

Journal of molecular biology 382(2):458, 2008 Oct 3 - Who cited this? | PubMed ID: 18674541 | Fulltext

Methods for reducing nonspecific interaction in antibody-antigen assay via atomic force microscopy.

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Wakayama J, Sekiguchi H, Akanuma S, Ohtani T, and Sugiyama S

Analytical biochemistry 380(1):51, 2008 Sep 1 - Who cited this? | PubMed ID: 18559251 | Fulltext

Dehydroascorbic acid uptake and intracellular ascorbic acid accumulation in cultured Müller glial cells (TR-MUL).

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Hosoya K, Nakamura G, Akanuma S, Tomi M, and Tachikawa M

Neurochemistry international 52(7):1351-7, 2008 Jun - Who cited this? | PubMed ID: 18353508 | Fulltext

ATP-binding cassette transporter A1 (ABCA1) deficiency does not attenuate the brain-to-blood efflux transport of human amyloid-beta peptide (1-40) at the blood-brain barrier.

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Akanuma S, Ohtsuki S, Doi Y, Tachikawa M, Ito S, Hori S, Asashima T, Hashimoto T, Yamada K, Ueda K, Iwatsubo T, and Terasaki T

Neurochemistry international 52(6):956-61, 2008 May - Who cited this? | PubMed ID: 18201804 | Fulltext

Expression of nuclear receptor mRNA and liver X receptor-mediated regulation of ABC transporter A1 at rat blood-brain barrier.

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Akanuma S, Hori S, Ohtsuki S, Fujiyoshi M, and Terasaki T

Neurochemistry international 52(4-5):669-74, 2008 - Who cited this? | PubMed ID: 17919779 | Fulltext

Identification and characterization of key substructures involved in the early folding events of a (beta/alpha)8-barrel protein as studied by experimental and computational methods.

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Akanuma S and Yamagishi A

Journal of molecular biology 353(5):1161-70, 2005 Nov 11 - Who cited this? | PubMed ID: 16216267 | Fulltext

A detailed unfolding pathway of a (beta/alpha)8-barrel protein as studied by molecular dynamics simulations.

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Akanuma S, Miyagawa H, Kitamura K, and Yamagishi A

Proteins 58(3):538-46, 2005 Feb 15 - Who cited this? | PubMed ID: 15614829 | Fulltext

Combinatorial mutagenesis to restrict amino acid usage in an enzyme to a reduced set.

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Akanuma S, Kigawa T, and Yokoyama S

Proceedings of the National Academy of Sciences of the United States of America 99(21):13549-53, 2002 Oct 15 - Who cited this? | PubMed ID: 12361984 | Fulltext

Design, X-ray crystallography, molecular modelling and thermal stability studies of mutant enzymes at site 172 of 3-isopropylmalate dehydrogenase from Thermus thermophilus.

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Qu C, Akanuma S, Tanaka N, Moriyama H, and Oshima T

Acta crystallographica. Section D, Biological crystallography 57(Pt 2):225-32, 2001 Feb - Who cited this? | PubMed ID: 11173468 | Fulltext

Stressful delivery influences circulating thrombopoietin (TPO) levels in newborns: possible role for cortisol in TPO-mpl binding.

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Ikeno K, Koike K, Takeshita A, Shinjo K, Higuchi T, Nakabayashi T, Akanuma S, Hizume K, Ishiguro A, Ogami K, Kato T, Miyazaki H, Ohno R, and Komiyama A

Early human development 58(3):225-35, 2000 Jun - Who cited this? | PubMed ID: 10936442 | Fulltext

Crystal structures of 3-isopropylmalate dehydrogenases with mutations at the C-terminus: crystallographic analyses of structure-stability relationships.

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Nurachman Z, Akanuma S, Sato T, Oshima T, and Tanaka N

Protein engineering 13(4):253-8, 2000 Apr - Who cited this? | PubMed ID: 10810156 | Fulltext

Further improvement of the thermal stability of a partially stabilized Bacillus subtilis 3-isopropylmalate dehydrogenase variant by random and site-directed mutagenesis.

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Akanuma S, Yamagishi A, Tanaka N, and Oshima T

European journal of biochemistry / FEBS 260(2):499-504, 1999 Mar - Who cited this? | PubMed ID: 10095787 | Fulltext

Serial increase in the thermal stability of 3-isopropylmalate dehydrogenase from Bacillus subtilis by experimental evolution.

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Akanuma S, Yamagishi A, Tanaka N, and Oshima T

Protein science : a publication of the Protein Society 7(3):698-705, 1998 Mar - Who cited this? | PubMed ID: 9541402 | Fulltext

Effect of polar side chains at position 172 on thermal stability of 3-isopropylmalate dehydrogenase from Thermus thermophilus.

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Akanuma S, Qu C, Yamagishi A, Tanaka N, and Oshima T

FEBS letters 410(2-3):141-4, 1997 Jun 30 - Who cited this? | PubMed ID: 9237617 | Fulltext

A mutation at the interface between domains causes rearrangement of domains in 3-isopropylmalate dehydrogenase.

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Qu C, Akanuma S, Moriyama H, Tanaka N, and Oshima T

Protein engineering 10(1):45-52, 1997 Jan - Who cited this? | PubMed ID: 9051733 | Fulltext

Spontaneous tandem sequence duplications reverse the thermal stability of carboxyl-terminal modified 3-isopropylmalate dehydrogenase.

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Akanuma S, Yamagishi A, Tanaka N, and Oshima T

Journal of bacteriology 178(21):6300-4, 1996 Nov - Who cited this? | PubMed ID: 8892833 | Fulltext

Further stabilization of 3-isopropylmalate dehydrogenase of an extreme thermophile, Thermus thermophilus, by a suppressor mutation method.

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Kotsuka T, Akanuma S, Tomuro M, Yamagishi A, and Oshima T

Journal of bacteriology 178(3):723-7, 1996 Feb - Who cited this? | PubMed ID: 8550506 | Fulltext

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