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Papers authored by Aird WC

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Critical Role for GATA3 in Mediating Tie2 Expression and Function in Large Vessel Endothelial Cells.

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Song H, Suehiro J, Kanki Y, Kawai Y, Inoue K, Daida H, Yano K, Ohhashi T, Oettgen P, Aird WC, Kodama T, and Minami T

The Journal of biological chemistry 284(42):29109-24, 2009 Oct 16 - Who cited this? | PubMed ID: 19674970 | Fulltext

The Down syndrome critical region gene 1 short variant promoters direct vascular bed-specific gene expression during inflammation in mice.

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Minami T, Yano K, Miura M, Kobayashi M, Suehiro J, Reid PC, Hamakubo T, Ryeom S, Aird WC, and Kodama T

The Journal of clinical investigation 119(8):2257-70, 2009 Aug - Who cited this? | PubMed ID: 19620774 | Fulltext

A +220 GATA motif mediates basal but not endotoxin-repressible expression of the von Willebrand factor promoter in Hprt-targeted transgenic mice.

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Liu J, Kanki Y, Okada Y, Jin E, Yano K, Shih SC, Minami T, and Aird WC

Journal of thrombosis and haemostasis : JTH 7(8):1384-92, 2009 Aug - Who cited this? | PubMed ID: 19496923 | Fulltext

Down's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1.

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Baek KH, Zaslavsky A, Lynch RC, Britt C, Okada Y, Siarey RJ, Lensch MW, Park IH, Yoon SS, Minami T, Korenberg JR, Folkman J, Daley GQ, Aird WC, Galdzicki Z, and Ryeom S

Nature 459(7250):1126-30, 2009 Jun 25 - Who cited this? | PubMed ID: 19458618 | Fulltext

Antiinflammatory effects of the ETS factor ERG in endothelial cells are mediated through transcriptional repression of the interleukin-8 gene.

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Yuan L, Nikolova-Krstevski V, Zhan Y, Kondo M, Bhasin M, Varghese L, Yano K, Carman CV, Aird WC, and Oettgen P

Circulation research 104(9):1049-57, 2009 May 8 - Who cited this? | PubMed ID: 19359602 | Fulltext

Molecular heterogeneity of tumor endothelium.

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Aird WC

Cell and tissue research 335(1):271-81, 2009 Jan - Who cited this? | PubMed ID: 18726119 | Fulltext

Skin biopsies demonstrate site-specific endothelial activation in mouse models of sepsis.

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Shapiro NI, Yano K, Sorasaki M, Fischer C, Shih SC, and Aird WC

Journal of vascular research 46(5):495-502, 2009 - Who cited this? | PubMed ID: 19346756 | Fulltext

Del-1, an endogenous leukocyte-endothelial adhesion inhibitor, limits inflammatory cell recruitment.

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Choi EY, Chavakis E, Czabanka MA, Langer HF, Fraemohs L, Economopoulou M, Kundu RK, Orlandi A, Zheng YY, Prieto DA, Ballantyne CM, Constant SL, Aird WC, Papayannopoulou T, Gahmberg CG, Udey MC,

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Science (New York, N.Y.) 322(5904):1101-4, 2008 Nov 14 - Who cited this? | PubMed ID: 19008446 | Fulltext

Elevated levels of placental growth factor represent an adaptive host response in sepsis.

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Yano K, Okada Y, Beldi G, Shih SC, Bodyak N, Okada H, Kang PM, Luscinskas W, Robson SC, Carmeliet P, Karumanchi SA, and Aird WC

The Journal of experimental medicine 205(11):2623-31, 2008 Oct 27 - Who cited this? | PubMed ID: 18852292 | Fulltext

Hepatocyte Growth Factor Inhibits VEGF-Forkhead-Dependent Gene Expression in Endothelial Cells.

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Abid MR, Nadeau RJ, Spokes KC, Minami T, Li D, Shih SC, and Aird WC

Arteriosclerosis, thrombosis, and vascular biology, 2008 Sep 11 - Who cited this? | PubMed ID: 18787186 | Fulltext

Gas6-Induced Signaling in Human Endothelial Cells is Mediated by FOXO1a.

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Ganopolsky JG, Abid R, Aird WC, and Blostein MD

Journal of thrombosis and haemostasis : JTH, 2008 Aug 1 - Who cited this? | PubMed ID: 18680538 | Fulltext

A GABP-binding element in the Robo4 promoter is necessary for endothelial expression in vivo.

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Okada Y, Jin E, Nikolova-Krstevski V, Yano K, Liu J, Beeler D, Spokes K, Kitayama M, Funahashi N, Doi T, Janes L, Minami T, Oettgen P, and Aird WC

Blood, 2008 Jun 2 - Who cited this? | PubMed ID: 18519813 | Fulltext

Ligand-independent assembly of purified soluble magic roundabout (Robo4), a tumor-specific endothelial marker.

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Yoshikawa M, Mukai Y, Okada Y, Yoshioka Y, Tsunoda SI, Tsutsumi Y, Okada N, Aird WC, Doi T, and Nakagawa S

Protein expression and purification, 2008 May 21 - Who cited this? | PubMed ID: 18571431 | Fulltext

Tumor necrosis factor-alpha enhances neutrophil adhesiveness: induction of vascular cell adhesion molecule-1 via activation of Akt and CaM kinase II and modifications of histone acetyltransferase and histone deacetylase 4 in human tracheal smooth muscle c.

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Lee CW, Lin CC, Luo SF, Lee HC, Lee IT, Aird WC, Hwang TL, and Yang CM

Molecular pharmacology 73(5):1454, 2008 May - Who cited this? | PubMed ID: 18227124 | Fulltext

A prospective, observational study of soluble FLT-1 and vascular endothelial growth factor in sepsis.

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Shapiro NI, Yano K, Okada H, Fischer C, Howell M, Spokes KC, Ngo L, Angus DC, and Aird WC

Shock (Augusta, Ga.) 29(4):452-7, 2008 Apr - Who cited this? | PubMed ID: 18598002 | Fulltext

Endothelium in health and disease.

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Aird WC

Pharmacological reports : PR 60(1):139-43, 2008 - Who cited this? | PubMed ID: 18276995 | Fulltext

Thrombin downregulates thrombomodulin expression and activity in primary human endothelial cells.

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Seguin C, Abid MR, Spokes KC, and Aird WC

Endothelium : journal of endothelial cell research 15(3):143-8, 2008 - Who cited this? | PubMed ID: 18568955 | Fulltext

Priming effect of homocysteine on inducible vascular cell adhesion molecule-1 expression in endothelial cells.

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Séguin C, Abid MR, Spokes KC, Schoots IG, Brkovic A, Sirois MG, and Aird WC

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 62(6):395-400, 2008 - Who cited this? | PubMed ID: 18406566 | Fulltext

NADPH oxidase activity selectively modulates vascular endothelial growth factor signaling pathways.

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Abid MR, Spokes KC, Shih SC, and Aird WC

The Journal of biological chemistry 282(48):35373-85, 2007 Nov 30 - Who cited this? | PubMed ID: 17908694 | Fulltext

G protein-coupled receptor Ca2+-linked mitochondrial reactive oxygen species are essential for endothelial/leukocyte adherence.

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Hawkins BJ, Solt LA, Chowdhury I, Kazi AS, Abid MR, Aird WC, May MJ, Foskett JK, and Madesh M

Molecular and cellular biology 27(21):7582, 2007 Nov - Who cited this? | PubMed ID: 17724077 | Fulltext

The history of the capillary wall: doctors, discoveries, and debates.

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Hwa C and Aird WC

American journal of physiology. Heart and circulatory physiology 293(5):H2667-79, 2007 Nov - Who cited this? | PubMed ID: 17693543 | Fulltext

Vascular bed-specific endothelium-dependent vasomomotor relaxation in the hagfish, Myxine glutinosa.

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Feng J, Yano K, Monahan-Earley R, Morgan ES, Dvorak AM, Sellke FW, and Aird WC

American journal of physiology. Regulatory, integrative and comparative physiology 293(2), 2007 Aug - Who cited this? | PubMed ID: 17537844 | Fulltext

Vascular bed-specific thrombosis.

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Aird WC

Journal of thrombosis and haemostasis : JTH 5 Suppl 1:283-91, 2007 Jul - Who cited this? | PubMed ID: 17635738 | Fulltext

A three-kilobase fragment of the human Robo4 promoter directs cell type-specific expression in endothelium.

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Okada Y, Yano K, Jin E, Funahashi N, Kitayama M, Doi T, Spokes K, Beeler DL, Shih SC, Okada H, Danilov TA, Maynard E, Minami T, Oettgen P, and Aird WC

Circulation research 100(12):1712, 2007 Jun 22 - Who cited this? | PubMed ID: 17495228 | Fulltext

Endothelium as a therapeutic target in sepsis.

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Aird WC

Current drug targets 8(4):501-7, 2007 Apr - Who cited this? | PubMed ID: 17430120 | Fulltext

Phenotypic heterogeneity of the endothelium: I. Structure, function, and mechanisms.

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Aird WC

Circulation research 100(2):158-73, 2007 Feb 2 - Who cited this? | PubMed ID: 17272818 | Fulltext

Phenotypic heterogeneity of the endothelium: II. Representative vascular beds.

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Aird WC

Circulation research 100(2):174-90, 2007 Feb 2 - Who cited this? | PubMed ID: 17272819 | Fulltext

Phenotypic heterogeneity is an evolutionarily conserved feature of the endothelium.

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Yano K, Gale D, Massberg S, Cheruvu PK, Monahan-Earley R, Morgan ES, Haig D, von Andrian UH, Dvorak AM, and Aird WC

Blood 109(2):613, 2007 Jan 15 - Who cited this? | PubMed ID: 16990601 | Fulltext

Histone deacetylase inhibitor reduces monocyte adhesion to endothelium through the suppression of vascular cell adhesion molecule-1 expression.

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Inoue K, Kobayashi M, Yano K, Miura M, Izumi A, Mataki C, Doi T, Hamakubo T, Reid PC, Hume DA, Yoshida M, Aird WC, Kodama T, and Minami T

Arteriosclerosis, thrombosis, and vascular biology 26(12):2652-9, 2006 Dec - Who cited this? | PubMed ID: 17008592 | Fulltext

A novel class of vascular endothelial growth factor-responsive genes that require forkhead activity for expression.

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Abid MR, Shih SC, Otu HH, Spokes KC, Okada Y, Curiel DT, Minami T, and Aird WC

The Journal of biological chemistry 281(46):35544-53, 2006 Nov 17 - Who cited this? | PubMed ID: 16980307 | Fulltext

Vascular endocan is preferentially expressed in tumor endothelium.

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Abid MR, Yi X, Yano K, Shih SC, and Aird WC

Microvascular research 72(3):136-45, 2006 Nov - Who cited this? | PubMed ID: 16956626 | Fulltext

Thrombin-induced autoinhibitory factor, Down syndrome critical region-1, attenuates NFAT-dependent vascular cell adhesion molecule-1 expression and inflammation in the endothelium.

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Minami T, Miura M, Aird WC, and Kodama T

The Journal of biological chemistry 281(29):20503-20, 2006 Jul 21 - Who cited this? | PubMed ID: 16627481 | Fulltext

Endothelium and allotransplantation.

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Aird WC

Transplantation 82(1 Suppl):S6-8, 2006 Jul 15 - Who cited this? | PubMed ID: 16829797 | Fulltext

Vascular endothelial growth factor is an important determinant of sepsis morbidity and mortality.

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Yano K, Liaw PC, Mullington JM, Shih SC, Okada H, Bodyak N, Kang PM, Toltl L, Belikoff B, Buras J, Simms BT, Mizgerd JP, Carmeliet P, Karumanchi SA, and Aird WC

The Journal of experimental medicine 203(6):1447-58, 2006 Jun 12 - Who cited this? | PubMed ID: 16702604 | Fulltext

Mechanisms of endothelial cell heterogeneity in health and disease.

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Aird WC

Circulation research 98(2):159-62, 2006 Feb 3 - Who cited this? | PubMed ID: 16456105 | Fulltext

Endothelial cell heterogeneity and atherosclerosis.

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Aird WC

Current atherosclerosis reports 8(1):69-75, 2006 Jan - Who cited this? | PubMed ID: 16455017 | Fulltext

Coagulation.

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Aird WC

Critical care medicine 33(12 Suppl):S485-7, 2005 Dec - Who cited this? | PubMed ID: 16340429 | Fulltext

Preconditioning of primary human endothelial cells with inflammatory mediators alters the "set point" of the cell.

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Wada Y, Otu H, Wu S, Abid MR, Okada H, Libermann T, Kodama T, Shih SC, Minami T, and Aird WC

The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 19(13):1914, 2005 Nov - Who cited this? | PubMed ID: 16172186 | Fulltext

Forkhead transcription factors inhibit vascular smooth muscle cell proliferation and neointimal hyperplasia.

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Abid MR, Yano K, Guo S, Patel VI, Shrikhande G, Spokes KC, Ferran C, and Aird WC

The Journal of biological chemistry 280(33):29864-73, 2005 Aug 19 - Who cited this? | PubMed ID: 15961397 | Fulltext

Thrombin, TNF-alpha, and LPS exert overlapping but nonidentical effects on gene expression in endothelial cells and vascular smooth muscle cells.

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Wu SQ and Aird WC

American journal of physiology. Heart and circulatory physiology 289(2):H873-85, 2005 Aug - Who cited this? | PubMed ID: 15833800 | Fulltext

Spatial and temporal dynamics of the endothelium.

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Aird WC

Journal of thrombosis and haemostasis : JTH 3(7):1392-406, 2005 Jul - Who cited this? | PubMed ID: 15892866 | Fulltext

Sepsis and coagulation.

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Aird WC

Critical care clinics 21(3):417-31, 2005 Jul - Who cited this? | PubMed ID: 15992665 | Fulltext

Endothelial cell gene regulation.

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Minami T and Aird WC

Trends in cardiovascular medicine 15(5):174-84, 2005 Jul - Who cited this? | PubMed ID: 16165014 | Fulltext

CpG oligodeoxynucleotide protection in polymicrobial sepsis is dependent on interleukin-17.

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Rice L, Orlow D, Ceonzo K, Stahl GL, Tzianabos AO, Wada H, Aird WC, and Buras JA

The Journal of infectious diseases 191(8):1368-76, 2005 Apr 15 - Who cited this? | PubMed ID: 15776385 | Fulltext

Endothelial biomedicine: its status as an interdisciplinary field, its progress as a basic science, and its translational bench-to-bedside gap.

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Hwa C, Sebastian A, and Aird WC

Endothelium : journal of endothelial cell research 12(3):139-51, 2005 - Who cited this? | PubMed ID: 16291517 | Fulltext

Vascular endothelial growth factor- and thrombin-induced termination factor, Down syndrome critical region-1, attenuates endothelial cell proliferation and angiogenesis.

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Minami T, Horiuchi K, Miura M, Abid MR, Takabe W, Noguchi N, Kohro T, Ge X, Aburatani H, Hamakubo T, Kodama T, and Aird WC

The Journal of biological chemistry 279(48):50537-54, 2004 Nov 26 - Who cited this? | PubMed ID: 15448146 | Fulltext

Vascular endothelial growth factor-mediated induction of manganese superoxide dismutase occurs through redox-dependent regulation of forkhead and IkappaB/NF-kappaB.

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Abid MR, Schoots IG, Spokes KC, Wu SQ, Mawhinney C, and Aird WC

The Journal of biological chemistry 279(42):44030-8, 2004 Oct 15 - Who cited this? | PubMed ID: 15308628 | Fulltext

Interaction between hex and GATA transcription factors in vascular endothelial cells inhibits flk-1/KDR-mediated vascular endothelial growth factor signaling.

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Minami T, Murakami T, Horiuchi K, Miura M, Noguchi T, Miyazaki J, Hamakubo T, Aird WC, and Kodama T

The Journal of biological chemistry 279(20):20626, 2004 May 14 - Who cited this? | PubMed ID: 15016828 | Fulltext

Endothelium as an organ system.

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Aird WC

Critical care medicine 32(5 Suppl):S271-9, 2004 May - Who cited this? | PubMed ID: 15118530 | Fulltext

Endothelial cells present antigens in vivo.

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Rothermel AL, Wang Y, Schechner J, Mook-Kanamori B, Aird WC, Pober JS, Tellides G, and Johnson DR

BMC immunology 5:5, 2004 Mar 16 - Who cited this? | PubMed ID: 15113397 | Fulltext

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