OBJECTIVE:: To estimate the effect of serial membrane sweeping on the onset of labor in women who planned
vaginal birth after cesarean (
VBAC). METHODS:: Women at term with one transverse lower segment
cesarean delivery who were suitable for and who planned
VBAC were approached to participate. Participants were
randomly assigned to weekly membrane sweeping or weekly
vaginal assessment for
Bishop score until delivery. Participants and delivery providers were blinded to the allocated treatment. Standard
obstetric care was given to all participants. The primary outcome was onset of labor which was defined as the presence of spontaneous regular and
painful contractions that cause
cervical dilation to at least 3 cm or
prelabor rupture of membranes. Secondary outcomes included
induction of labor and repeat
cesarean delivery. RESULTS:: One hundred eight women were
randomly assigned to membrane sweeping and 105 to control. The spontaneous labor rate was 78.5% compared with 72.1% (
relative risk [RR] 1.1, 95%
confidence interval [CI] 0.9-1.3; P=.34), the
induction of labor rate was 12.1% compared with 9.6% (RR 1.3, 95% CI 0.6-2.8; P=.66), and the all-cause
cesarean delivery rate was 40.2% compared with 44.2% (RR 0.9, 95% CI 0.7-1.2; P=.58) for the membrane sweeping and control groups, respectively.
Gestational age at delivery (
mean+/-
standard deviation) of 39.6+/-1.0 weeks for the membrane sweeping group compared with 39.6+/-0.9 weeks for the control group (P=.84) was no different. CONCLUSION:: Serial membrane sweeping at term in women who planned
VBAC has no significant effect on the onset of labor,
pregnancy duration,
induction of labor, or repeat
cesarean delivery. CLINICAL TRIAL REGISTRATION:: ISRCTN, isrctn.org, ISRCTN55163179. LEVEL OF EVIDENCE:: I.