Organocatalytic enantioselective synthesis of nitrogen-substituted dihydropyran-...

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Organocatalytic enantioselective synthesis of nitrogen-substituted dihydropyran-2-ones, a key synthetic intermediate of 1beta-methylcarbapenems.
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Organocatalytic enantioselective cycloadditions providing nitrogen-substituted dihydropyran-2-ones were developed in two catalytic systems. The (3R,4R)-product was a versatile intermediate in the synthesis of 1beta-methylcarbapenem antibiotics.
Organic letters 11(17):3934-7, 2009 Sep 3 - Who cited this? | PubMed ID: 19658429 | Fulltext
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