A potentiometric detector, based on electrodeposition of
polypyrrole onto Pt
electrode, was investigated in this study. The
chromatographic performance of the
PPy detector was investigated in
ion chromatography. The resulting
PPy detector exhibited good performance for AA determination with a wide linear range (1.0 x 10(-6) to 1.0 x 10(-2)M), a highly
reproducible response (R.S.D. of 2.45%), without any interference and long-term stability. The calculated detection limit was 7.0 x 10(-5)mM at 3 sigma. The calibration results showed good Nernstian behavior and also satisfactory low detection limit. In order to verify the reliability of the
PPy detector, it was applied to the determination of AA in
pharmaceutical samples. The results were satisfactory and agreed closely with the manufacturers' stated contents. The
PPy electrode can be used as an alternative novel potentiometric detector material for determination of AA in standards and
pharmaceutical samples.
