A novel modifier of regulatory T cells.

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A novel modifier of regulatory T cells.
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The receptor for the lipid mediator sphingosine 1-phosphate is critical for T cell trafficking. New data show that signaling mediated by this receptor critically controls the development, maintenance and suppressive activity of natural regulatory T cells that express the transcription factor Foxp3.
Ohkura N and Sakaguchi S
Nature immunology 10(7):685-6, 2009 Jul - Who cited this? | PubMed ID: 19536192 | Fulltext
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