AIM: Report a new case of primary Synovialosarcoma. CASE: We report a case of a 16 year old girl, who presented with a tumefaction on the right
clavicle evolving for 3 months. Various explorations carried out, in particular
thoracic scanner and imagery by magnetic
resonance, showed a multilocular
cystic formation of the seat and the
clavicle reaching the
mediastinum. A
pathological examination of the part (piece) highlighted a biphasic synovialosarcoma of grade III. This diagnosis was validated by the
immunohistochemistry study and the detection of transcribed specific fusion of the synovialosarcoma, SYT-SSX1. CONCLUSION: The unusual locations of the primitive SS must be known because the diversity of their
microscopic aspects may cause
confusion in the diagnosis. The
immunohistochemistry, and more recently the
cytogenetic studies, helps to solve these problems of differential diagnosis.
