Protein Quality Control: On IPODs and Other JUNQ.

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Protein Quality Control: On IPODs and Other JUNQ.
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The accumulation of misfolded cytosolic or aggregation-prone proteins leads to cellular stress. To protect the cell, damaged or aggregated proteins are actively sequestered in two newly discovered quality control compartments, JUNQ and IPOD, which are highly conserved in evolution.
Bagola K and Sommer T
Current biology : CB 18(21):R1019-21, 2008 Nov 11 - Who cited this? | PubMed ID: 19000801 | Fulltext
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